Dr. Raúl Oscar Cosentino
Genome Specialist
Research Topics: Antigenic variation, cell-to-cell heterogeneity, genomic variation.
Key methods: single-cell RNA-sequencing, Cas9-based perturbation screens, NGS data analysis.
Contact
Phone: +49 (0)89 2180 71156
Email: raul.cosentino@lmu.de
Links
Education
2014 PhD in Molecular Biology and Biotechnology
San Martin National University, Buenos Aires, Argentina
2009 BSc in Biotechnology
San Martin National University, Buenos Aires, Argentina
Key Publications
Beaver AK, Keneskhanova Z, Cosentino RO, Weiss BL, Awuoche EO, Smallenberger GM, Buenconsejo GY, Crilly NP, Smith JE, Hakim JMC, Zhang B, Bobb B, Rijo-Ferreira F, Figueiredo LM, Aksoy S, Siegel TN, Mugnier MR. (2024) Tissue spaces are reservoirs of antigenic diversity for Trypanosoma brucei. Nature. doi: 10.1038/s41586-024-08151-z
Cosentino RO, Brink BG, Siegel TN. (2021) Allele-specific assembly of a eukaryotic genome corrects apparent frameshifts and reveals a lack of nonsense-mediated mRNA decay. NAR Genomics and Bioinformatics. doi: 10.1093/nargab/lqab082
Müller LSM*, Cosentino RO*, Förstner KU, Guizetti J, Wedel C, Kaplan N, Janzen CJ, Arampatzi P, Vogel J, Steinbiss S, Otto TD, Saliba AE, Sebra RP, Siegel TN. (2018) Genome organization and DNA accessibility control antigenic variation in trypanosomes. Nature. doi: 10.1038/s41586-018-0619-8
Cosentino RO, Agüero F. (2014) Genetic profiling of the isoprenoid and sterol biosynthesis pathway genes of Trypanosoma cruzi. PloS One. doi: 10.1371/journal.pone.0096762
Cosentino RO, Agüero F. (2012) A simple strain typing assay for Trypanosoma cruzi: discrimination of major evolutionary lineages from a single amplification product. PloS Negl Trop Dis. doi: 10.1371/journal.pntd.0001777
* indicates equal contribution