Genome Assemblies
For the Trypanosoma brucei Lister 427 strain.

For the Trypanosoma brucei Lister 427 strain.
© Siegel Lab
Full Name: Tb427v12
Changes since the last version
- 85 of the 103 remaining gaps in the genome were closed.
- 74 regions were identified to be missized. 63 of them have been corrected.
- Centromeres were annotated.
- Transcription start site annotations on chromosome 9 were corrected (they were shifted by ~15kb before).
Links
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Zenodo (details and versions)
Github (the used code)
Manuscript
Rabuffo C, Schmidt MR, Yadav P, Tong P, Carloni R, Barcons-Simon A, Cosentino RO, Krebs S, Matthews KR, Allshire RC, Siegel TN* (2024)
Inter-chromosomal transcription hubs shape the 3D genome architecture of African trypanosomes.
Nature Communications 15: 10716 doi: 10.1038/s41467-024-55285-9
Full Name: Tb427v11
Changes since the last version
- to be filled in
Links
Download files (direct download)
Zenodo (details and versions)
Github (the used code)
This version is available on TriTrypDB.
Full Name: Tb427v10 / TriTrypDB-43_TbruceiLister427_2018
Changes since the last version
-to be filled in
Links
Download files (direct download)
Zenodo (details and versions)
Manuscript
Cosentino RO*, Brink BG, Siegel TN* (2021)
Allele-specific assembly of a eukaryotic genome corrects apparent frameshifts and reveals a lack of nonsense-mediated mRNA decay
NAR Genomics and Bioinformatics doi.org/10.1093/nargab/lqab082
© Siegel Lab
Full Name: Tb427v9
Changes since the last version
- to be filled in
Links
Download files (direct download)
Zenodo (details and versions)
Manuscript
Müller LSM#, Cosentino RO#, Förstner KU, Guizetti J, Wedel C, Kaplan N, Janzen CJ, Arampatzi P, Vogel J, Steinbiss S, Otto TD, Saliba A-E, Sebra RP, Siegel TN* (2018)
Genome organization and DNA accessibility control antigenic variation in trypanosomes.
Nature 563: 121–125 doi.org/10.1038/s41586-018-0619-8