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Decoding the impact of nuclear organization on antigenic variation in parasites.
31 Jul 2023
Our review describes the importance of 3D genome architecture in the regulation of antigen expression.
Together with Mark Carrington (University of Cambridge), we reviewed key aspects of antigenic variation, placing a strong focus on the role of 3D genome architecture in regulating antigen expression.
Barcons-Simon A, Carrington M, Siegel TN* (2023)
Decoding the impact of nuclear organization on antigenic variation in parasites
Nature Microbiology 8: 1408-1418 doi: 10.1038/s41564-023-01424-9
# equal contribution
* corresponding authors
members of the Siegel lab are listed in bold