Publications
Gras Lab Publications :
2025
von Knoerzer-Suckow J, Aden EH, Haase R, Klingl A, Forné I, Gras S. Plasma membrane recycling drives reservoir formation during Toxoplasma gondii intracellular replication. PLoS Biol. 2025 Sep 30;23(9):e3003415. doi: 10.1371/journal.pbio.3003415.
von Knoerzer-Suckow Julia, Sazegar Parnian, Periz Javier, Gras Simon, Meissner Markus (2025) Tracking maternal proteins uncovers a central role for the residual body in organelle recycling during Toxoplasma gondii replication eLife 14:RP108685 https://doi.org/10.7554/eLife.108685.1
Li, W., Koczy, O., Qin, P., Forne, I., Gras, S., Gruenert, J., Klingl, A., Mattei, S., Jimenez-Ruiz, Ec* and Meissner, Mc*. An apical ring protein essential for conoid complex assembly and daughter cell formation in Toxoplasma gondii. Nat Commun 16, 10149 (2025). doi: 10.1038/s41467-025-65382-y
Grech J, Sinde AP, Periz J, Singer M, Gras S, Forné I, Klingl A, Dacks JB, Jimenez-Ruiz Ec* and Meissner Mc*. Tepsin and AP4 Mediate Transport from the trans-Golgi to the Plant-Like Vacuole in Toxoplasma. Journal of Cell Biology. 2025. Dec 1;224(12): e202312109. doi: 10.1083/jcb.202312109
2023
Ludek Koreny, Brandon N. Mercado-Saavedra, Christen M. Klinger, Konstantin Barylyuk, Simon Butterworth, Jennifer Hirst, Yolanda Rivera-Cuevas, Nathan R. Zaccai, Victoria J. C. Holzer, Andreas Klingl, Joel B. Dacks, Vern B. Carruthers, Margaret S. Robinson, Simon Gras* & Ross F. Waller; Stable endoytic structures navigate the complex pellicle of apicomplexan parasites. Nature Communications volume 14, Article number: 2167 (2023) DOI: 10.1038/s41467-023-37431-x
2020
Spielmann T, Gras S, Sabitzki R, Meissner M.; Endocytosis in Plasmodium and Toxoplasma Parasites. Trends Parasitol. 2020, Jun;36(6):520-532.Epub 2020 Apr 24. PMID: 32340866 Review. DOI: 10.1016/j.pt.2020.03.010
Previous publications:
2019
Gras S*, Jimenez-Ruiz E, Klinger CM, Schneider K, Klingl A, Lemgruber L, Meissner M.; An endocytic-secretory cycle participates in Toxoplasma gondii in motility. In: PLOS Biology 2019, DOI: 10.1371/journal.pbio.3000060
Periz J, Del Rosario M, McStea A, Gras S, Loney C, Wang L, Martin-Fernandez ML, Meissner M.; A highly dynamic F-actin network regulates transport and recycling of micronemes in Toxoplasma gondii vacuoles. Nat Commun. 2019 Sep 13;10(1):4183. PMID: 31519913 Free PMC article. DOI: 10.1038/s41467-019-12136-2
2017
Jamie A Whitelaw , Fernanda Latorre-Barragan , Simon Gras , Gurman S Pall , Jacqueline M Leung , Aoife Heaslip , Saskia Egarter , Nicole Andenmatten , Shane R Nelson , David M Warshaw , Gary E Ward , Markus Meissner.; Surface attachment, promoted by the actomyosin system of Toxoplasma gondii is important for efficient gliding motility and invasion. BMC Biology, 2017, 15, 1; PMID:28100223; PMCID:PMC5242020 DOI: 10.1186/s12915-016-0343-5
Periz J, Whitelaw J, Harding C, Gras S, Del Rosario Minina MI, Latorre-Barragan F, Lemgruber L, Reimer MA, Insall R, Heaslip A, Meissner M.; Toxoplasma gondii F-actin forms an extensive filamentous network required for material exchange and parasite maturation. Elife. 2017 Mar 21;6:e24119. PMID: 28322189 Free PMC article DOI: 10.7554/eLife.24119
Gras S, Jackson A, Woods S, Pall G, Whitelaw J, Leung JM, Ward GE, Roberts CW and Meissner M.; Parasites lacking the micronemal protein MIC2 are deficient in surface attachment and host cell egress, but remain virulent in vivo. Wellcome Open Research, 2017, 2, 32.; PMID:28630943; PMCID:PMC5473411 DOI: 10.12688/wellcomeopenres.11594.2
2014
Gras, S., Byzia, A., Gilbert, F. B., McGowan, S., Drag, M., Silvestre, A., Brossier, F. (2014). Aminopeptidase N1 (EtAPN1), an M1 metalloprotease of the apicomplexan parasite Eimeria tenella, participates in parasite development. Eukaryot Cell, 13(7), 884-895. DOI: 10.1128/EC.00062-14
2012
Rieux, A., Gras, S., Lecaille, F., Niepceron, A., Katrib, M., Smith, N. C., Brossier, F. (2012). Eimeripain, a cathepsin B-like cysteine protease, expressed throughout sporulation of the apicomplexan parasite Eimeria tenella. PLoS One, 7(3), e31914. DOI: 10.1371/journal.pone.0031914