Plasma membrane labelling of Toxoplasma gondii tachyzoites

Gras Laboratory

Endocytosis, recycling, and plasma membrane dynamics of the apicomplexan parasite Toxoplasma gondii

The Gras Lab is a junior research group established in 2021. Initially funded by the DFG with its first PhD student, the lab aims to expand in the coming years. Multiple articles are being written based on the work from this initial funding phase.

The Gras lab is a member of the Faculty of Veterinary Medicine at the LMU Munich. We are associated with the Chair of Experimental Parasitology (Prof. Markus Meissner) in Lena-Christ-Str. 48, 82152 Planegg-Martinsried

Intracellular tachyzoites of Toxoplasma gondii

Image Gallery

Here you will find a collection of nice images taken throughout our studies.

  1. Intracellular tachyzoites of Toxoplasma gondii
  2. Plasma membrane labelling of Toxoplasma gondii tachyzoites
  3. Visualisation of the plasma membrane reservoir of Toxoplasma gondii tachyzoites using ultra-expansion microscopy

Toxoplasma gondii tachyzoites during replication imaged using an Elyra microscope from Zeiss. Yellow: Microtubules, Red: Micronemes, Cyan: DNA. Picture by : Simon Gras, LMU Munich

© Simon Gras

The surface antigen SAG1, present on the parasite plasma membrane (PM-SAG1 : Magenta) and inside the parasite (Int-SAG1:Green), was labeled prior to invasion. Endocytosis of PM-SAG1 and secretion of Int-SAG1 can be observed during the replication of the parasite. Picture by: Simon Gras, LMU Munich

© LMU / Simon Gras

Expansion Microscopy of RH parasites labelled with SAG-1 antibodies. The yellow arrows indicate the plasma membrane reservoir (PMR) formed by the parasite during the replication process. Picture by: Romuald Haase, University of Geneva

© Romuald Haase

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